Naturally Inspired | Scientifically Defined

Specialist in plant derived cell signalling small molecules to address
challenging medical conditions for humans and companion animals

UPDATES


STELFONTA® USA Marketing Authorisation Progress

21 September 2020

The US Food and Drug Administration - Center for Veterinary Medicine (FDA-CVM) has concluded that all technical sections for the STELFONTA (tigilanol tiglate) application for marketing authorisation are complete.


QBiotics announces clinical collaboration with MSD targeting unresectable melanoma

13 August 2020

MSD collaboration to investigate QBiotics’ lead molecule tigilanol tiglate in combination with KEYTRUDA® (pembrolizumab)


QBiotics doses first Australian patient in Phase I/II clinical trial for head and neck cancer

22 July 2020

First Australian patient successfully dosed with tigilanol tiglate at The Kinghorn Cancer Centre, as part of QBiotics’ Phase I/II clinical trial in patients with Head and Neck Squamous Cell Carcinoma (HNSCC).


QBiotics commercialises first tigilanol tiglate pharmaceutical product with launch of STELFONTA®

27 April 2020

Australian life sciences company, QBiotics Group Limited (QBiotics) has commercialised the first product for its lead compound, tigilanol tiglate, with the launch of STELFONTA® in the European markets at the Virbac Oncology Summit Webinar Event (24 April 2020).


QBiotics receives first registration for tigilanol tiglate with European Medicines Agency approval of STELFONTA®

20 January 2020

STELFONTA® (tigilanol tiglate) has been approved by the European Medicines Agency (EMA), making it the first pharmaceutical treatment available for all grades of canine non-metastatic mast cell tumours (MCT). The approval marks the first registration of QBiotics' lead compound tigilanol tiglate, which is also under review by the US Food and Drug Administration - Center for Veterinary Medicine (FDA-CVM) and the Australian Pesticides and Veterinary Medicines Authority (APVMA).


The first in-human Clinical Phase I study of intratumoural tigilanol tiglate has been published in The Lancet's EBioMedicine journal

10 December 2019

An efficacious dose was achieved and a Maximum Tolerated Dose (MTD) was not reached, indicating tigilanol tiglate tolerability in humans. Promising outcomes were attained in patients with a variety of solid tumour types, with a 27% treatment response, including 18% complete response (full tumour destruction). Following these positive results, a Phase I/II trial of tigilanol tiglate in patients with Head and Neck Squamous Cell Carcinoma (HNSCC) is underway, with the first patient successfully dosed.